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Thử nghiệm có đối chứng với giả dược về thuốc ức chế PCSK9 đường uống Enlicitide

A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide

N Engl J Med. 2026 Feb 5;394(6):529-539. doi: 10.1056/NEJMoa2511002.
Ann Marie Navar; Elina Mikhailova; Alberico L Catapano; Puja Banka; Dirk J Blom; Alberto Cadena; Susan Kourpanidis; Norman E Lepor; Kazuhisa Tsukamoto; Geraldine Mendizabal; Julio Nunez; Wenjuan Zhang… Ann Marie Navar; Elina Mikhailova; Alberico L Catapano; Puja Banka; Dirk J Blom; Alberto Cadena; Susan Kourpanidis; Norman E Lepor; Kazuhisa Tsukamoto; Geraldine Mendizabal; Julio Nunez; Wenjuan Zhang; Pengfei Zhu; Min Zhuo; Christie M Ballantyne; CORALreef Lipids Investigators; Harold E Bays; Robert Sidney Rosenson; Lance A Rudolph; William D Yarbrough; Nabil S Andrawis; William B Smith; Drew Purdy; Judith Lee Kirsten; Julio Cesar Vijil; Barbara E Rizzardi; Robert Carmen Cupelo; Luis Ignacio De La Cruz; Michael J Lillestol; Mark S Adams; Ashwini Gore; Paul Gerard Matherne; Nidal Morrar; George Hartley Freeman; David J Morin; Michael J Koren; Kenneth Blaze; Ronald Stumbris; Seth J Baum; David Funt; Michael Hafran; Larry Reed; Phillip D Toth; John Keith Scott; Sady Armada Alpizar; Allan Larcena; Atoya Adams; Shishir Kumar Khetan; Elysa Shaw; Norman Elliott Lepor; Abel Murillo; Alan Jan Kivitz; Amit G Shah; David Ramstad; Samir Abdelshaheed; Michael T Ledet; Pedro P Ylisastigui; Paul Grena; Mary C L Bailey; Douglas Scott Denham; Elliot Shin; Mohammed Allaw; Michael Adams; Christie Mitchell Ballantyne; Dan Lender; Jeffrey D Wayne; Frances Eileen Broyles; Sheryl M Marks; Walter Faggett; Marisa Liliana Vico; Sonia Angelica Sassone; Sergio Andres Nemi; Maria Cristina De Salvo; Elizabeth Gelersztein; Angela Maria Romero Zarante; Alberto Jose Cadena; Carlos Eduardo Alcala; Juan Esteban Gomez-Mesa; Miguel Alfredo Moncada Corredor; James Junior Eastmond; Arnold Mendez; Carlos Augusto Yepes; Guillermo Gonzalez Galvez; Carlos Alberto Aguilar Salinas; Isabelle Ulrike Schenkenberger; Nikolaos Perakakis; Karsten Milek; Harald Lapp; Ursula Rauch-Kroehnert; Georg Plaßmann; Maguli Barel; Yoseph Caraco; Hofit Cohen; Ronen Durst; Dov Gavish; Gil Moravsky; Victor Vishlitzky; Shadi Hamoud; Alon Eisen; Gaetano M De Ferrari; José Pablo Werba; Giorgio Sesti; Saverio Muscoli; Salvatore Piro; Piera Angelica Merlini; Farzahna Mohamed; Charlotte Maxeke; Qasim Ebrahim Bhorat; Zarinah Mohamed; Nyda Fourie; Lesley Jean Burgess; Dirk Jacobus Blom; Silvia Narejos Perez; Carlos Guijarro Heerraiz; Agustin Blanco Echevarria; Jose Ramon Gonzalez-Juanatey; Julio Nunez Villota; Esteban Jodar Gimeno; Cristobal Jesus Morales Portillo; Rafael Jesús Hidalgo Urbano; Jose Luis Diaz Diaz; Oguz Abdullah Uyaroglu; Hulya Cicekcioglu; Latife Meral Kayikcioglu; Yuksel Cavusoglu; Tayfun Sahin; Fatma Dogruel; Seung-Hyuk Choi; Hyun-Jae Kang; Sang-Hak Lee; Chang-Wook Nam; Duk-Woo Park; In-Ho Chae; Myeong-Ho Yoon; Gyu Chul Oh; Byung-Su Yoo; ByungJin Kim; Doo-Il Kim; Woong Gil Choi; Jung-Hyun Choi; Jong Sung Park; Doo Sun Sim; Chau-Chung Wu; Kai-Chien Yang; Chien-Hsun Hsia; Cheng-I Cheng; Jhih Yuan Shih; Po-Hsun Huang; Ting-Hsing Chao; Chun-Yao Huang; Changsheng Ma; Yibin Mei; Aidong Shen; Jiyan Chen; Min D Eng; Zhihua Fang; Jianqiang Peng; Mingya Liu; Zhiyu Ling; Shao Jiang; Jia Sun; Jianxiong Liu; Qiufang Lian; Lun Li; Yuan Ji; Keping Yang; Zhaohui Pei; Xiongwei Xie; Satoshi Inoue; Osamu Matsuoka; Daisaku Masuda; Yasushi Fukushima; Arihiro Kiyosue; Tamio Teramoto; Ikuo Inoue; Takahiro Saeki; Mitsutoshi Kato; Takeshi Osonoi; Kazuo Kanno; Terumasa Nagase; Yoshihide Hirohata; Toshihiko Shiraiwa; Koki Shin; Nobuo Shiode; Masahiro Sugawara; Toshihiko Hashimoto; Kyoichi Mizuno; Takeshi Yamashita; Kunio Hirano; Yodo Gatate; Takafumi Nishida; Yuta Shirai; James De Lemos; Martha Gulati; Robert A Harrington; Shamir Mehta; Laine Thomas; Christie M Ballantyne; Alberico L Catapano; Ann Marie Navar; Gabriel Philippe Steg; Erik Stroes; Ann Marie Navar; Elina Mikhailova; Alberico L Catapano; Puja Banka; Dirk J Blom; Alberto Cadena; Susan Kourpanidis; Norman E Lepor; Kazuhisa Tsukamoto; Geraldine Mendizabal; Julio Nunez; Wenjuan Zhang; Pengfei Zhu; Min Zhuo; Christie M Ballantyne; CORALreef Lipids Investigators; Harold E Bays; Robert Sidney Rosenson; Lance A Rudolph; William D Yarbrough; Nabil S Andrawis; William B Smith; Drew Purdy; Judith Lee Kirsten; Julio Cesar Vijil; Barbara E Rizzardi; Robert Carmen Cupelo; Luis Ignacio De La Cruz; Michael J Lillestol; Mark S Adams; Ashwini Gore; Paul Gerard Matherne; Nidal Morrar; George Hartley Freeman; David J Morin; Michael J Koren; Kenneth Blaze; Ronald Stumbris; Seth J Baum; David Funt; Michael Hafran; Larry Reed; Phillip D Toth; John Keith Scott; Sady Armada Alpizar; Allan Larcena; Atoya Adams; Shishir Kumar Khetan; Elysa Shaw; Norman Elliott Lepor; Abel Murillo; Alan Jan Kivitz; Amit G Shah; David Ramstad; Samir Abdelshaheed; Michael T Ledet; Pedro P Ylisastigui; Paul Grena; Mary C L Bailey; Douglas Scott Denham; Elliot Shin; Mohammed Allaw; Michael Adams; Christie Mitchell Ballantyne; Dan Lender; Jeffrey D Wayne; Frances Eileen Broyles; Sheryl M Marks; Walter Faggett; Marisa Liliana Vico; Sonia Angelica Sassone; Sergio Andres Nemi; Maria Cristina De Salvo; Elizabeth Gelersztein; Angela Maria Romero Zarante; Alberto Jose Cadena; Carlos Eduardo Alcala; Juan Esteban Gomez-Mesa; Miguel Alfredo Moncada Corredor; James Junior Eastmond; Arnold Mendez; Carlos Augusto Yepes; Guillermo Gonzalez Galvez; Carlos Alberto Aguilar Salinas; Isabelle Ulrike Schenkenberger; Nikolaos Perakakis; Karsten Milek; Harald Lapp; Ursula Rauch-Kroehnert; Georg Plaßmann; Maguli Barel; Yoseph Caraco; Hofit Cohen; Ronen Durst; Dov Gavish; Gil Moravsky; Victor Vishlitzky; Shadi Hamoud; Alon Eisen; Gaetano M De Ferrari; José Pablo Werba; Giorgio Sesti; Saverio Muscoli; Salvatore Piro; Piera Angelica Merlini; Farzahna Mohamed; Charlotte Maxeke; Qasim Ebrahim Bhorat; Zarinah Mohamed; Nyda Fourie; Lesley Jean Burgess; Dirk Jacobus Blom; Silvia Narejos Perez; Carlos Guijarro Heerraiz; Agustin Blanco Echevarria; Jose Ramon Gonzalez-Juanatey; Julio Nunez Villota; Esteban Jodar Gimeno; Cristobal Jesus Morales Portillo; Rafael Jesús Hidalgo Urbano; Jose Luis Diaz Diaz; Oguz Abdullah Uyaroglu; Hulya Cicekcioglu; Latife Meral Kayikcioglu; Yuksel Cavusoglu; Tayfun Sahin; Fatma Dogruel; Seung-Hyuk Choi; Hyun-Jae Kang; Sang-Hak Lee; Chang-Wook Nam; Duk-Woo Park; In-Ho Chae; Myeong-Ho Yoon; Gyu Chul Oh; Byung-Su Yoo; ByungJin Kim; Doo-Il Kim; Woong Gil Choi; Jung-Hyun Choi; Jong Sung Park; Doo Sun Sim; Chau-Chung Wu; Kai-Chien Yang; Chien-Hsun Hsia; Cheng-I Cheng; Jhih Yuan Shih; Po-Hsun Huang; Ting-Hsing Chao; Chun-Yao Huang; Changsheng Ma; Yibin Mei; Aidong Shen; Jiyan Chen; Min D Eng; Zhihua Fang; Jianqiang Peng; Mingya Liu; Zhiyu Ling; Shao Jiang; Jia Sun; Jianxiong Liu; Qiufang Lian; Lun Li; Yuan Ji; Keping Yang; Zhaohui Pei; Xiongwei Xie; Satoshi Inoue; Osamu Matsuoka; Daisaku Masuda; Yasushi Fukushima; Arihiro Kiyosue; Tamio Teramoto; Ikuo Inoue; Takahiro Saeki; Mitsutoshi Kato; Takeshi Osonoi; Kazuo Kanno; Terumasa Nagase; Yoshihide Hirohata; Toshihiko Shiraiwa; Koki Shin; Nobuo Shiode; Masahiro Sugawara; Toshihiko Hashimoto; Kyoichi Mizuno; Takeshi Yamashita; Kunio Hirano; Yodo Gatate; Takafumi Nishida; Yuta Shirai; James De Lemos; Martha Gulati; Robert A Harrington; Shamir Mehta; Laine Thomas; Christie M Ballantyne; Alberico L Catapano; Ann Marie Navar; Gabriel Philippe Steg; Erik Stroes

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