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Sacituzumab Govitecan kết hợp với Pembrolizumab trong điều trị ung thư vú bộ ba âm tính tiến triển

Sacituzumab Govitecan plus Pembrolizumab for Advanced Triple-Negative Breast Cancer

N Engl J Med. 2026 Jan 22;394(4):354-366. doi: 10.1056/NEJMoa2508959.
Sara M Tolaney; Evandro de Azambuja; Kevin Kalinsky; Sherene Loi; Sung-Bae Kim; Clinton Yam; Bernardo Rapoport; Seock-Ah Im; Barbara Pistilli; Wassim Mchayleh; David W Cescon; Junichiro Watanabe; Manu… Sara M Tolaney; Evandro de Azambuja; Kevin Kalinsky; Sherene Loi; Sung-Bae Kim; Clinton Yam; Bernardo Rapoport; Seock-Ah Im; Barbara Pistilli; Wassim Mchayleh; David W Cescon; Junichiro Watanabe; Manuel Alejandro Lara Bañuelas; Ruffo Freitas-Junior; Javier Salvador Bofill; Maryam Afshari; Dianna Gary; Lu Wang; Catherine Lai; Peter Schmid; ASCENT-04/KEYNOTE-D19 Clinical Trial Investigators; Diego Lucas Kaen; Ernesto Korbenfeld; Rubén Dario Kowalyszyn; Maria Valeria Cáceres; Mario Micheri; Felipe Palazzo; Peter Savas; Wen Xu; Belinda Yeo; Jodi Lynch; Catherine Shannon; Frances Boyle; Meena Okera; Daniel Egle; Clemens Dormann; Hans Wildiers; Eline Naert; Roberto Hegg; Ruffo De Freitas-Junior; Giuliano Borges; Debora Gagliato; Maria Fernanda Biazotto Fernandes; Alessandra Morelle; Luciana Landeiro; Carlos Escosteguy Barrios; Fábio André Franke; Patricia Beato; Lilian Arruda do Rêgo Barros; David Cescon; Katarzyna Jerzak; Marc Webster; David Fenton; Nathalie LeVasseur; Stephen Chia; Jennifer Friedmann; Christine Brezden-Masley; Xinni Song; Eduardo Patricio Yañez Ruiz; Pablo Rodríguez Monarca; Felipe Pinto; Marcelo Garrido; Pamela Victoria Salman Boghikian; Monica Ahumada Olea; Katarína Petrakova; Renata Soumarová; Martina Zimovjanova; Olivier Tredan; Marie-Ange Mouret-Reynier; Barbara Pistilli; Alain Lortholary; Laura Mansi; Frederic Viret; Florence Dalenc; Nelly Firmin; Cristian Villanueva; Christelle Levy; Tobias Engler; Hans-Christian Kolberg; Andreas Schneeweiss; Holger Schultz; Volkmar Müller; Claus Hanusch; Maggie Banys-Paluchowski; Monika Graeser; Wolfram Malter; Joanne Chiu; Chun-Chung Yau; Ting Ying Ng; Gabor Laszlo Rubovszky; István Sipocz; Shai Ayelet; Einav Gal-Yam; Rinat Yerushalmi; Daniela Katz; Hadar Goldvaser; Amir Sonnenblick; Shani Paluch-Shimon; Alessandra Fabi; Michelino De Laurentiis; Rebecca Pedersini; Laura Biganzoli; Giulia Bianchi; Valentina Guarneri; Claudio Zamagni; Editta Baldini; Marco Colleoni; Junichiro Watanabe; Takanori Ishida; Toshinari Yamashita; Norikazu Masuda; Michiko Tsuneizumi; Naoki Hayashi; Tomomi Fujisawa; Kenjiro Aogi; Takahiro Nakayama; Mitsuya Itoh; Tadahiko Shien; Kenzo Shimazu; Toru Mukohara; Seiichiro Nishimura; Shigenori Nagai; Tomoyuki Yoshiyama; Choong Swee Hsia; Mastura Yusof; Ng Nyek Ping; Adlinda Alip; Vaishnavi Jeyasingam; Daniel Motola Kuba; Manuel Alejandro; Lara Bañuelas; Mario Alberto Sanchez Prieto; Emilio Murillo Ramirez; Flavia Morales Vasquez; Jessica Gricelda Reyes Contreras; Paola Marianela Balancan Zapata; Tomas Daniel Pineda Razo; Erika Castillo Gutierrez; Luis Contreras; Joan Heijns; Agnes Jager; Lisanne Hamming; Janine Nuver; Zbigniew Nowecki; Jacek Jassem; Barbara Radecka; Sung-Bae Kim; Seock-Ah Im; Joo Hyuk Sohn; Yeon Hee Park; Ji-Eun Lee; Keun Seok Lee; Jee Hyun Kim; Andrea Wong; Bernardo Rapoport; Shane Cullis; Francisco Javier Salvador Bofill; Lourdes Calvo Martinez; Mafalda Oliveira; Olga Martinez-Saez; Serafin Morales Murillo; Cristina Arqueros Nunez; Javier Cortés Castán; Yann Izarzugaza Peron; Laura Garcia Estevez; Francisco Ayala de la Peña; Javier Pascual; Begoña Bermejo De Las Heras; Sara Lopez-Tarruella; Urs Breitenstein; Jens Huober; Tsu-Yi Chao; Wei-Pang Chung; Chiun-Sheng Huang; Shang-Wen Chen; Shou-Tung Chen; Yesim Eralp; Ahmet Bilici; Cagatay Arslan; Nuri Karadurmus; Cengiz Karacin; Umut Demirci; Ozgur Ozyilkan; Peter Schmid; Elisavet Papadimitraki; Clinton Yam; Sara Robinson; Gregory Vidal; Wassim Mchayleh; Kelly McCann; Sara Hurvitz; Stephanie Graff; Adam Brufsky; Denise Yardley; Steven Papish; Joyce A O'Shaughnessy; Coral Omene; Priyanka Sharma; Amelia Zelnak; Michael A Danso; Roberto Leon-Ferre; Vasileios Assikis; Jeffrey Hargis; Abiola Ibraheem; Rebecca Shatsky; Aisha Ahmed; William Gradishar; Sara M Tolaney; Evandro de Azambuja; Kevin Kalinsky; Sherene Loi; Sung-Bae Kim; Clinton Yam; Bernardo Rapoport; Seock-Ah Im; Barbara Pistilli; Wassim Mchayleh; David W Cescon; Junichiro Watanabe; Manuel Alejandro Lara Bañuelas; Ruffo Freitas-Junior; Javier Salvador Bofill; Maryam Afshari; Dianna Gary; Lu Wang; Catherine Lai; Peter Schmid; ASCENT-04/KEYNOTE-D19 Clinical Trial Investigators; Diego Lucas Kaen; Ernesto Korbenfeld; Rubén Dario Kowalyszyn; Maria Valeria Cáceres; Mario Micheri; Felipe Palazzo; Peter Savas; Wen Xu; Belinda Yeo; Jodi Lynch; Catherine Shannon; Frances Boyle; Meena Okera; Daniel Egle; Clemens Dormann; Hans Wildiers; Eline Naert; Roberto Hegg; Ruffo De Freitas-Junior; Giuliano Borges; Debora Gagliato; Maria Fernanda Biazotto Fernandes; Alessandra Morelle; Luciana Landeiro; Carlos Escosteguy Barrios; Fábio André Franke; Patricia Beato; Lilian Arruda do Rêgo Barros; David Cescon; Katarzyna Jerzak; Marc Webster; David Fenton; Nathalie LeVasseur; Stephen Chia; Jennifer Friedmann; Christine Brezden-Masley; Xinni Song; Eduardo Patricio Yañez Ruiz; Pablo Rodríguez Monarca; Felipe Pinto; Marcelo Garrido; Pamela Victoria Salman Boghikian; Monica Ahumada Olea; Katarína Petrakova; Renata Soumarová; Martina Zimovjanova; Olivier Tredan; Marie-Ange Mouret-Reynier; Barbara Pistilli; Alain Lortholary; Laura Mansi; Frederic Viret; Florence Dalenc; Nelly Firmin; Cristian Villanueva; Christelle Levy; Tobias Engler; Hans-Christian Kolberg; Andreas Schneeweiss; Holger Schultz; Volkmar Müller; Claus Hanusch; Maggie Banys-Paluchowski; Monika Graeser; Wolfram Malter; Joanne Chiu; Chun-Chung Yau; Ting Ying Ng; Gabor Laszlo Rubovszky; István Sipocz; Shai Ayelet; Einav Gal-Yam; Rinat Yerushalmi; Daniela Katz; Hadar Goldvaser; Amir Sonnenblick; Shani Paluch-Shimon; Alessandra Fabi; Michelino De Laurentiis; Rebecca Pedersini; Laura Biganzoli; Giulia Bianchi; Valentina Guarneri; Claudio Zamagni; Editta Baldini; Marco Colleoni; Junichiro Watanabe; Takanori Ishida; Toshinari Yamashita; Norikazu Masuda; Michiko Tsuneizumi; Naoki Hayashi; Tomomi Fujisawa; Kenjiro Aogi; Takahiro Nakayama; Mitsuya Itoh; Tadahiko Shien; Kenzo Shimazu; Toru Mukohara; Seiichiro Nishimura; Shigenori Nagai; Tomoyuki Yoshiyama; Choong Swee Hsia; Mastura Yusof; Ng Nyek Ping; Adlinda Alip; Vaishnavi Jeyasingam; Daniel Motola Kuba; Manuel Alejandro; Lara Bañuelas; Mario Alberto Sanchez Prieto; Emilio Murillo Ramirez; Flavia Morales Vasquez; Jessica Gricelda Reyes Contreras; Paola Marianela Balancan Zapata; Tomas Daniel Pineda Razo; Erika Castillo Gutierrez; Luis Contreras; Joan Heijns; Agnes Jager; Lisanne Hamming; Janine Nuver; Zbigniew Nowecki; Jacek Jassem; Barbara Radecka; Sung-Bae Kim; Seock-Ah Im; Joo Hyuk Sohn; Yeon Hee Park; Ji-Eun Lee; Keun Seok Lee; Jee Hyun Kim; Andrea Wong; Bernardo Rapoport; Shane Cullis; Francisco Javier Salvador Bofill; Lourdes Calvo Martinez; Mafalda Oliveira; Olga Martinez-Saez; Serafin Morales Murillo; Cristina Arqueros Nunez; Javier Cortés Castán; Yann Izarzugaza Peron; Laura Garcia Estevez; Francisco Ayala de la Peña; Javier Pascual; Begoña Bermejo De Las Heras; Sara Lopez-Tarruella; Urs Breitenstein; Jens Huober; Tsu-Yi Chao; Wei-Pang Chung; Chiun-Sheng Huang; Shang-Wen Chen; Shou-Tung Chen; Yesim Eralp; Ahmet Bilici; Cagatay Arslan; Nuri Karadurmus; Cengiz Karacin; Umut Demirci; Ozgur Ozyilkan; Peter Schmid; Elisavet Papadimitraki; Clinton Yam; Sara Robinson; Gregory Vidal; Wassim Mchayleh; Kelly McCann; Sara Hurvitz; Stephanie Graff; Adam Brufsky; Denise Yardley; Steven Papish; Joyce A O'Shaughnessy; Coral Omene; Priyanka Sharma; Amelia Zelnak; Michael A Danso; Roberto Leon-Ferre; Vasileios Assikis; Jeffrey Hargis; Abiola Ibraheem; Rebecca Shatsky; Aisha Ahmed; William Gradishar

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