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Tenecteplase so với điều trị nội khoa tiêu chuẩn cho tắc động mạch nền trong vòng 24 giờ (TRACE-5): một thử nghiệm lâm sàng pha 3, vượt trội, nhãn mở, ngẫu nhiên, tiến cứu, mù phân tích kết cục, đa trung tâm

Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial

Lancet. 2026 Feb 21;407(10530):763-772. doi: 10.1016/S0140-6736(25)02633-9.
Yunyun Xiong; Fana Alemseged; Zhixin Cao; Lee H Schwamm; Si Zhang; Mark W Parsons; Marc Fisher; Yahui Hao; Aoming Jin; Jinfeng Yin; Yong Jiang; Fengyuan Che; Lihua Wang; Li Zhou; Hongguo Dai; Yutie Zh… Yunyun Xiong; Fana Alemseged; Zhixin Cao; Lee H Schwamm; Si Zhang; Mark W Parsons; Marc Fisher; Yahui Hao; Aoming Jin; Jinfeng Yin; Yong Jiang; Fengyuan Che; Lihua Wang; Li Zhou; Hongguo Dai; Yutie Zhao; Chunmiao Duan; Shuangzhe Wu; Ganghua Feng; Lixia Zong; Wanxing Ye; Ziran Wang; Ziqi Xu; Hao Wang; Manjun Hao; Yujie Ma; Xia Meng; Hao Li; Zixiao Li; Yilong Wang; Liping Liu; Xingquan Zhao; Bruce C V Campbell; Yongjun Wang; TRACE-5 investigators; Yunyun Xiong; Fana Alemseged; Zhixin Cao; Lee H Schwamm; Si Zhang; Mark W Parsons; Marc Fisher; Yahui Hao; Aoming Jin; Jinfeng Yin; Yong Jiang; Fengyuan Che; Lihua Wang; Li Zhou; Hongguo Dai; Yutie Zhao; Chunmiao Duan; Shuangzhe Wu; Ganghua Feng; Lixia Zong; Wanxing Ye; Ziran Wang; Ziqi Xu; Hao Wang; Manjun Hao; Yujie Ma; Xia Meng; Hao Li; Zixiao Li; Yilong Wang; Liping Liu; Xingquan Zhao; Bruce C V Campbell; Yongjun Wang; Yuzhang Bei; Xiaoxi Yao; Xiangchen Zhou; Feng Wang; Hongling Guo; Jinglin Yuan; Junfeng Zhao; Yanqiu Du; Ying Liu; Jinzhao He; Tingting Zhang; Xing Fang; Yanbo Huang; Zhaolong Peng; Di Zhong; Jianxin Xu; Shaoguang Wu; Tao Zhang; Xuying He; Haitao Wang; Guosheng Han; Weiying Di; Muhui Lin; Qianqian Qiu; Wei Zhang; Xiaomin Xiong; Xuewen Liu; Yanna Ma; Zhitao Zong; Guanglei Li; Jie Liu; Zhe Lv; Zongtao Liu; Changsong Wu; Chunlei Li; Guoping Ma; Guoshuai Yang; Guozhi Lu; Honghao Man; Jing Ding; Kai Hui; Shibin Wen; Xiangjun Ji; Xinxia Zhao; Yingzhuo Zang; Ziqi Xu; Cai Zhang; Min Zhao; Ping Sun; Qi Chen; Rui Zhao; Ruiyi Wang; Wei Wu; Xiaolong Tian; Xiaosong Li; Xin Wang; Yanping Guo; Yanxin Wang; Yongqian Lei; Zhihua Hao; Yunyun Xiong; Fana Alemseged; Zhixin Cao; Lee H Schwamm; Si Zhang; Mark W Parsons; Marc Fisher; Yahui Hao; Aoming Jin; Jinfeng Yin; Yong Jiang; Fengyuan Che; Lihua Wang; Li Zhou; Hongguo Dai; Yutie Zhao; Chunmiao Duan; Shuangzhe Wu; Ganghua Feng; Lixia Zong; Wanxing Ye; Ziran Wang; Ziqi Xu; Hao Wang; Manjun Hao; Yujie Ma; Xia Meng; Hao Li; Zixiao Li; Yilong Wang; Liping Liu; Xingquan Zhao; Bruce C V Campbell; Yongjun Wang; TRACE-5 investigators; Yunyun Xiong; Fana Alemseged; Zhixin Cao; Lee H Schwamm; Si Zhang; Mark W Parsons; Marc Fisher; Yahui Hao; Aoming Jin; Jinfeng Yin; Yong Jiang; Fengyuan Che; Lihua Wang; Li Zhou; Hongguo Dai; Yutie Zhao; Chunmiao Duan; Shuangzhe Wu; Ganghua Feng; Lixia Zong; Wanxing Ye; Ziran Wang; Ziqi Xu; Hao Wang; Manjun Hao; Yujie Ma; Xia Meng; Hao Li; Zixiao Li; Yilong Wang; Liping Liu; Xingquan Zhao; Bruce C V Campbell; Yongjun Wang; Yuzhang Bei; Xiaoxi Yao; Xiangchen Zhou; Feng Wang; Hongling Guo; Jinglin Yuan; Junfeng Zhao; Yanqiu Du; Ying Liu; Jinzhao He; Tingting Zhang; Xing Fang; Yanbo Huang; Zhaolong Peng; Di Zhong; Jianxin Xu; Shaoguang Wu; Tao Zhang; Xuying He; Haitao Wang; Guosheng Han; Weiying Di; Muhui Lin; Qianqian Qiu; Wei Zhang; Xiaomin Xiong; Xuewen Liu; Yanna Ma; Zhitao Zong; Guanglei Li; Jie Liu; Zhe Lv; Zongtao Liu; Changsong Wu; Chunlei Li; Guoping Ma; Guoshuai Yang; Guozhi Lu; Honghao Man; Jing Ding; Kai Hui; Shibin Wen; Xiangjun Ji; Xinxia Zhao; Yingzhuo Zang; Ziqi Xu; Cai Zhang; Min Zhao; Ping Sun; Qi Chen; Rui Zhao; Ruiyi Wang; Wei Wu; Xiaolong Tian; Xiaosong Li; Xin Wang; Yanping Guo; Yanxin Wang; Yongqian Lei; Zhihua Hao

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